Spicy Creamy Seafood Pasta

This Cajun Shrimp Alfredo combines the perfect balance of creamy Alfredo sauce with bold Cajun spices, tender steak slices, and juicy shrimp. The dish comes together in just 45 minutes, making it ideal for both weeknight dinners and special occasions when you want to impress without spending hours in the kitchen.

I first created this recipe when my in-laws visited unexpectedly one evening. It was such a hit that it's now our go-to celebration dish. The combination of tender steak and succulent shrimp makes everyone feel like they're dining at a fancy restaurant.

Ingredients

• Boneless sirloin steak 1 lb thinly sliced for quick and even cooking
• Shrimp 1 lb peeled and deveined choose large or jumbo for best texture
• Olive oil helps seal in flavors and prevents sticking
• Paprika adds smoky depth and beautiful color
• Cayenne pepper brings the signature Cajun heat adjust to your preference
• Garlic powder infuses savory flavor throughout
• Black pepper adds necessary warmth and bite
• Cream of mushroom soup creates a rich base without the fuss
• Milk thins the sauce to perfect consistency
• Parmesan cheese adds nutty depth and thickens the sauce naturally
• Dried oregano brings an herbal note that complements seafood
• Penne pasta holds the creamy sauce perfectly in its ridges

Step-by-Step Instructions

Pasta Preparation

Cook the penne pasta according to package directions until al dente usually about 10 minutes. Remember to generously salt your pasta water it should taste like the sea. This is your only chance to season the pasta itself. Drain but do not rinse to keep the starches that help sauce adhere.

Seasoning the Proteins

Create your Cajun spice mixture by combining olive oil, paprika, garlic powder, cayenne, and black pepper in a bowl. The oil helps the spices adhere to the proteins and creates a flavorful crust. Make sure to coat each piece of steak and shrimp thoroughly for maximum flavor.

Cooking the Steak

Heat a cast iron skillet or heavy pan until very hot. Add the seasoned steak in a single layer working in batches if necessary to avoid overcrowding. Cook for 2 to 3 minutes per side for medium rare or longer if desired. The high heat will create a flavorful crust while keeping the inside tender. Rest the meat for at least 5 minutes before slicing.

Sautéing the Shrimp

In the same skillet to capture all the flavors cook the seasoned shrimp. They only need about 2 minutes per side until they turn pink and opaque. Be careful not to overcook or they will become rubbery. Remove immediately when done.

Creating the Alfredo Sauce

In a large skillet combine cream of mushroom soup, milk, Parmesan, oregano, garlic powder, and black pepper. Simmer over medium heat for 15 to 20 minutes stirring frequently with a wooden spoon to prevent sticking. The sauce should coat the back of a spoon when ready.

Combining Components

Return the cooked steak and shrimp to the skillet with the Alfredo sauce. Gently fold them in to coat completely with the creamy sauce. The proteins will impart additional flavor to the sauce creating a harmonious blend.

Final Assembly

Add the cooked penne to the sauce mixture and toss everything together using tongs until every piece of pasta is well coated. If the sauce seems too thick add a splash of pasta cooking water to loosen it up. The starch in the water will help the sauce cling to the pasta.

Serving

Plate immediately while hot garnishing with fresh parsley or additional grated Parmesan. The contrast of the creamy sauce with the spiced proteins is best enjoyed fresh from the stove.

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The secret to this dish is actually the cream of mushroom soup. I discovered this shortcut when I ran out of heavy cream one night, and I think it actually adds more depth of flavor than traditional Alfredo. My husband always asks if I used my "special sauce" whenever I make this dish.

Make Ahead Options

This Cajun Shrimp and Steak Alfredo can be partially prepared ahead of time to make dinner even quicker. Season and cook the proteins up to a day in advance, and refrigerate them separately. The pasta can be cooked until just under al dente, tossed with a tiny bit of oil, and refrigerated. When ready to serve, prepare the sauce and warm all components together. The sauce may need an extra splash of milk to reach the right consistency after reheating.

Perfect Pairings

This rich and spicy pasta pairs beautifully with simple sides that offer contrast. A crisp green salad with a light vinaigrette cuts through the creaminess perfectly. Roasted asparagus or garlic bread also make excellent accompaniments. For drinks, try a crisp white wine like Pinot Grigio or a light beer to balance the richness of the dish.

Customization Ideas

This recipe is incredibly versatile and can be adapted to suit your preferences or what you have on hand. Chicken works wonderfully instead of steak for a lighter option. For a vegetarian version, substitute mushrooms and bell peppers for the proteins. If you prefer a lighter sauce, replace half the cream of mushroom soup with chicken broth. You can also add vegetables like spinach, peas, or roasted red peppers for extra nutrition and color.

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Recipe FAQs

→ Can I substitute the protein in this Cajun Alfredo?

Absolutely! While the steak and shrimp combination is delicious, you can easily substitute with just chicken, all shrimp, or even salmon. For vegetarian options, try adding roasted vegetables like bell peppers, zucchini, and mushrooms to maintain the hearty texture and flavor profile.

→ How spicy is this Cajun pasta dish?

This dish has a moderate heat level from the paprika and cayenne pepper. For milder flavor, reduce the cayenne by half or omit it completely. To increase the spice level, add additional cayenne pepper or a dash of hot sauce to the Alfredo sauce while simmering.

→ What pasta shapes work best with this sauce?

While penne is specified, any medium pasta shape works well. Fettuccine is traditional with Alfredo sauce and holds the creamy sauce beautifully. Other excellent options include rigatoni, farfalle (bow ties), or cavatappi, as their shapes and ridges capture the rich sauce effectively.

→ Can I make this Cajun Alfredo ahead of time?

You can prepare components ahead of time, but for best results, assemble just before serving. The sauce can be made up to 2 days ahead and stored in the refrigerator. The protein can be seasoned and cooked 1 day ahead. When ready to serve, reheat the sauce gently, cook fresh pasta, and combine with the warmed protein.

→ What sides pair well with this pasta dish?

This rich pasta pairs beautifully with light, fresh sides. Consider a simple green salad with vinaigrette, steamed asparagus, roasted broccoli, or garlic bread to soak up extra sauce. For wine pairing, try a crisp Pinot Grigio or Sauvignon Blanc to balance the richness of the Alfredo sauce.

→ How can I make this dish without cream of mushroom soup?

For a from-scratch alternative, make a roux with 2 tablespoons each of butter and flour, then gradually whisk in 1 cup heavy cream and 1 cup chicken broth. Add sautéed mushrooms if desired. Simmer until thickened, then add the Parmesan cheese and seasonings as directed in the original instructions.